Everyone's journey to parenthood is unique, but if you're struggling with unexplained infertility, it's only natural to consider other fertility options, such as assisted reproductive technologies.
While exploring fertility treatment options, you may have come across EVIE IUI. But what sets EVIE IUI apart from standard intrauterine insemination (IUI), and is it the right choice for you?
What is EVIE IUI?
EVIE IUI, also known as Slow Release Intra-Uterine Insemination (SRI), uses a small, single-use mechanical pump (“Evie”) to slowly release prepared sperm into the uterus over four hours via a balloon catheter and an insemination syringe.
Unlike standard IUI, where sperm are injected in one go, EVIE mimics natural conception by slowly and gently releasing them, which is designed to release prepared sperm gradually into the uterus over several hours.
What is the difference between standard IUI and EVIE IUI?
| Standard IUI | EVIE IUI (slow release) | |
|---|---|---|
| Sperm release | Injected all in one go | Gradually released over four hours |
| Device | Simple catheter and syringe | Single-use pump with balloon catheter |
| Timing | Takes minutes | You will need to wear it for four hours |
| Approach | Delivers sperm quickly | Gradual release of prepared sperm over several hours |
| Patient comfort | May cause brief cramping | Some individuals may experience mild cramping during the procedure |
Should I get an EVIE IUI instead of a standard IUI?
EVIE IUI may be considered in certain situations, depending on your fertility profile and your doctor’s clinical assessment. This may include cases where one or more of the following apply:
A couple with unexplained infertility
Your male partner has mild male subfertility
You have endometriosis (grade 1 or 2) and have intact fallopian tubes
You has cervical mucus problem
Your male partner has anti-sperm antibodies
Ejaculation is not possible due to erectile dysfunction or vaginismus (involuntary vaginal muscle tightening).
Retrograde ejaculation (where the semen travel backwards in the bladder)
If you are unsure whether standard IUI or EVIE IUI may be more appropriate for your fertility journey, a fertility specialist at Thomson Medical can help you understand your options based on your individual circumstances. Request an appointment with Thomson Medical today.
How can I prepare for an EVIE IUI?
b\The preparation for an EVIE IUI procedure will be similar to the preparation for a standard IUI procedure. You will need a thorough medical exam and fertility tests. Your partner will be examined and tested as well. This could include:
A uterine exam
Ultrasounds of your uterus
Screening for sexually transmitted infections (STIs) and other infectious diseases
Blood tests
Your fertility specialist may recommend taking folic acid, which is included in most prenatal vitamins, for at least three months before trying to conceive or starting IUI treatment.
Remember to also:
Attend all pre-treatment appointments:
Your fertility specialist will assess your suitability and discuss timing.
Follow medication instructions:
Ovulation-inducing drugs may be prescribed, as with other IUI cycles.
Dress comfortably:
During EVIE IUI, the device is strapped to your thigh for four hours.
Plan light activities:
You can carry out light duties (walking, light household tasks), but avoid vigorous movement.
What is the process of getting an EVIE IUI like?
Upon your arrival, the sperm will have already been prepared, a process that typically takes around an hour. The actual EVIE procedure lasts about 15 minutes and is similar to a standard IUI or routine exams like a smear test. It is noted for being performed differently from treatments such as IVF or ICSI.
A thin catheter is gently inserted into the uterus, making it a quick and straightforward process. You might feel mild cramping, similar to regular IUI. Your doctor might recommend a mild pain reliever to ease any discomfort.
Once the EVIE device is positioned, the doctor will record the "start time" and "end time" and guide you through the simple removal process after four hours. You will receive a copy of these times along with removal instructions.
The EVIE procedure is designed to be performed as an outpatient procedure. After the device is set and activated, you can leave the clinic. Although you can drive and walk, it is advisable to relax comfortably for the four-hour duration as advised by your healthcare professional.
Avoid making sudden vigorous movements with the device or catheter during the process. Bathroom visits are allowed, but it's best to avoid bowel movements if possible to reduce infection risk. Physical exertion and intercourse should be postponed until after removing the device. The doctor will offer detailed instructions and provide you with a guide for the removal process.
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How much does an EVIE IUI cost?
The costs may vary depending on the clinic, medications, and medical examinations required.
In private fertility centres, the cost of a single standard IUI cycle may vary, typically ranging from SGD 1,800 to SGD 3,000. This amount usually includes doctor consultation fees, injections, ultrasound scans, hormonal medications (hCG), and blood tests.
Subsequent cycles within six months may cost around SGD 700 to SGD 900. Some clinics offer more affordable packages starting at SGD 880 to SGD 1,000, but these often exclude additional costs for medications and medical exams.
Additional costs for diagnostic tests such as semen analysis or hormone testing can add SGD 96 to SGD 600 depending on the complexity of the tests required. Medications and ovulation induction injections may also increase the overall cost by up to SGD 2,000 per cycle.
The costs for an EVIE IUI should be similar to what is mentioned above. However, it is best to discuss directly with your healthcare provider for the most accurate pricing.
Financial assistance options
MediSave
Couples can use Medisave to offset IUI costs. Withdrawal limits are:
SGD 6,000 for the first cycle
SGD 5,000 for the second cycle
SGD 4,000 for subsequent cycles
The lifetime withdrawal limit for assisted reproductive treatments is capped at SGD 15,000 per couple.
Government co-funding
Singaporean couples undergoing IUI at public hospitals may qualify for government co-funding if they meet specific criteria:
Couples below 40 years old
Assessed by a doctor as suitable for IUI before IVF
At least one spouse is a Singaporean citizen
You have not previously received 3 co-funded fresh and 3 co-funded frozen cycles
Co-funding covers up to three cycles based on the citizenship status of the couple:
75% (up to SGD 1,000) for Singaporean couples
55% (up to SGD 700) for Singaporean and PR couples
35% (up to SGD 500) for Singaporean and foreigner couples
The prices mentioned above reflect current policies as of July 2025. However, please note that the prices of both IUI and the government co-funding are subject to change. For the most accurate pricing, please visit the MOH website to learn more about Medisave coverage and government co-funding options available to you.
FAQ
Are there any risks to an EVIE IUI?
The risks associated with EVIE IUI are generally similar to those of standard IUI, including mild cramping or discomfort during the procedure and a small risk of infection.
The slow-release method used in EVIE IUI has been suggested to reduce immunological reactions and lower the likelihood of polyspermia, where more than one sperm fertilises an egg. Your fertility specialist can advise whether this approach is suitable for your individual circumstances.
Can I immediately go back to my normal activities after an EVIE IUI?
Yes, light activities are permitted during the four-hour insemination period. Avoid strenuous exercise, sudden movement, or intercourse on the day of the procedure. Most people can resume daily routines right after finishing the treatment.
What are the advantages of an EVIE IUI?
Some individuals may find EVIE IUI suitable because:
It uses a slow-release method to deliver prepared sperm into the uterus over a longer period of time.
It may be considered as an alternative to standard IUI in selected cases, depending on the individual’s fertility profile and treatment plan.
The procedure is generally performed without the need for hospital admission.
After the device is fitted, you may usually continue with light daily activities during the treatment period, based on your doctor’s advice.
What are the disadvantages of an EVIE IUI?
Some considerations to keep in mind include:
EVIE IUI may cost more than standard IUI, depending on the clinic and treatment plan.
It may not be available at all fertility centres.
The device is typically worn for around four hours, and you may be advised to avoid vigorous activity during that time.
Can you pick gender with IUI?
No, IUI, including the EVIE technique, cannot reliably select the gender of a baby. Gender selection requires more advanced technologies available through IVF with genetic screening.
What factors may influence treatment outcomes with IUI?
Published figures from some studies have reported pregnancy rates of around 5–10% per treatment cycle for standard IUI in women under 35. For EVIE IUI, some studies have reported pregnancy rates of around 17–20% per treatment cycle in selected women under 35. Treatment outcomes can vary depending on age, fertility profile and individual clinical circumstances.
The information provided is intended for general guidance only and should not be considered medical advice. For personalised recommendations and tailored advice based on your unique situations, please consult a specialist at Thomson Medical. Request an appointment with Thomson Medical today.
For more information, contact us:
Thomson Fertility
- Paragon: 6252 7766
- Novena: 6399 3758, 8811 0358 (WA)
Thomson Specialists (Women's Health)
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