Dreaming of starting a family but facing challenges with natural conception? If male infertility is holding you back, IUI with donor sperm can be a gentle, supportive option to help you move forward.
What is IUI with donor sperm?
Intrauterine insemination (IUI) with donor sperm, also known as artificial insemination, is a type of fertility treatment that involves placing sperm from a carefully screened donor directly into the uterus during ovulation.
This increases the chances of fertilisation by bringing the sperm closer to the egg. IUI is a safe, non-invasive, and more affordable option compared to in vitro fertilisation (IVF), making it a popular choice for single women and those facing male infertility.
Important note: Single women and same-sex couples are currently not eligible for donor sperm treatments locally and often seek options abroad through private clinics. For more information on Singapore’s sperm donation regulations, please refer to the Ministry of Health’s guidelines.
How does sperm donation work in Singapore?
In Singapore, sperm donation is strictly regulated by the Ministry of Health (MOH) to ensure safety and ethical standards. Here are the key facts:
Anonymous donors only:
The identity of the sperm donor is kept confidential and cannot be disclosed.
Comprehensive screening:
Donors undergo detailed screening, including medical history checks, genetic testing, STI screening, and psychological evaluation.
Sperm sample collection:
Approved donors are asked to provide a sperm sample through masturbation in a private room at the clinic or sperm bank. The sample is collected into a sterile container for analysis.
Semen sample analysis:
The sperm sample is evaluated for volume, sperm count, motility (movement), and morphology (shape) to determine if it meets quality standards for donation.
Sperm quarantine:
Donated sperm is stored for at least six months before use, ensuring it is safe and disease-free.
Use of imported sperm:
Due to the limited availability of local donors, most clinics use donor sperm from MOH-approved international sperm banks.
Eligibility restrictions:
As of 2024, only married heterosexual couples are allowed to undergo assisted reproduction treatments in Singapore.
Counselling is mandatory as part of the programme to prepare couples emotionally and address issues such as donor anonymity, disclosure to the child in the future, and long-term psychological considerations.
Requirements to become sperm donor
Sperm donors must meet strict eligibility criteria to ensure the health and safety of both the recipient and future child. Typically, donors are:
Aged between 21 and 41 years old
In good physical and mental health
Thoroughly screened for genetic conditions, infectious diseases, family medical history, and lifestyle factors
Required to provide non-identifying details such as ethnicity, education level, blood type, and physical characteristics
In Singapore, each donor is permitted to father no more than three children through this programme. This guideline helps reduce the risk of accidental sexual relationships between children conceived from the same donor. Moreover, all sperm donations must be altruistic. Donors cannot be financially compensated for their contribution, ensuring the programme remains ethical and voluntary.
These safety measures ensure that only qualified and healthy individuals are accepted as sperm donors, giving recipients peace of mind.
Who is IUI with donor sperm suitable for?
IUI with donor sperm is a recommended fertility option for individuals and couples who are unable to conceive using a male partner’s sperm. This treatment may be suitable for:
Couples facing severe male infertility, such as azoospermia or genetic abnormalities
Couples where the male partner carries a hereditary condition that could be passed on
Those with repeated unsuccessful fertility treatments using the partner’s sperm
In some cases, IVF may be recommended instead of II, particularly for older patients or those with additional female factor infertility. A fertility specialist can advise on the best pathway.
Considering IUI with donor sperm? Request an appointment with Thomson Fertility Centre today to speak with our fertility specialists and explore your personalised options.
Fertility specialists at Thomson
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What to expect after IUI with donor sperm?
After undergoing IUI with donor sperm, it’s natural to watch for early signs of pregnancy, but remember, it's important to manage expectations and avoid testing too soon.
Early signs of conception
Some women may experience mild symptoms, including:
Cramping or light spotting (possible implantation bleeding)
Breast tenderness
Fatigue or tiredness
Nausea
Frequent urination
Mild bloating
These symptoms can closely resemble premenstrual signs and are not a definitive indicator of pregnancy. Avoid testing too early, as it can lead to unnecessary stress.
When to take a pregnancy test
Wait 14 days after your IUI procedure before taking a home pregnancy test or visiting your clinic for a blood test
Testing earlier may lead to a false negative, as hormone levels may not be high enough to detect
If your period is late or symptoms persist, you can request an appointment with us, and our fertility specialists can assist you with your next steps.
FAQ
Can IUI be done with donor sperm?
Yes, IUI can be done with donor sperm. It is a safe, widely used, and effective fertility option for individuals or couples who are unable—or choose not—to use sperm from a male partner.
What is the best way to get pregnant with a sperm donor?
Using high-quality, medically screened donor sperm
Accurately timing insemination, often with ovulation tracking or a trigger shot
Maintaining good uterine and ovulatory health
Choosing the right method—IUI or IVF—based on age, fertility history, and medical advice
Consulting a fertility specialist will help determine the best approach for your individual needs.
What is the success rate of IUI with donor sperm?
15–20% success rate per cycle
40–60% cumulative success over 3 to 6 cycles
Higher success rates are seen in women under 35 with regular menstrual cycles and no other fertility issues
Other important factors include accurate timing of ovulation, good uterine health, and sperm quality. Fortunately, donor sperm is typically of high quality due to strict screening standards.
Can you use your husband’s sperm for IUI?
Yes, IUI can be performed using your husband’s sperm. It is commonly used in cases of mild male infertility, unexplained infertility, or when timing needs to be optimised for conception.
What are the risks of donor insemination?
Mild discomfort or cramping after the procedure
Low risk of infection due to sterile techniques
Emotional considerations around donor anonymity
Risk of multiple pregnancy if fertility medications are used
Discussing these risks with a fertility specialist can help you make an informed decision.
Can you pick gender with IUI?
If you're considering IUI as a fertility treatment option, request a consultation with our fertility specialists at the Thomson Fertility Centre for personalised recommendations and tailored advice.
The information provided is intended for general guidance only and should not be considered medical advice. For personalised recommendations and tailored advice, please consult a specialist at Thomson Medical. Request an appointment with Thomson Medical today.
For more information, contact us:
Thomson Fertility Centre
- Paragon: 6252 7766
Thomson Specialists (Women's Health)
Request an Appointment