Non-Invasive Prenatal Tests (NIPT)

The test identifies more than 99% of fetuses with trisomy 21, which causes Down Syndrome

NIPT analyses cell-free DNA circulating in the pregnant mother’s blood. It is a new option in prenatal screening for Down syndrome (trisomy 21) and other common fetal chromosomal conditions (trisomies 18 and 13). As no invasive procedure is required in obtaining the sample, there is no risk of miscarriage.

The test identifies more than 99% of fetuses with trisomy 21, more than 96% of fetuses with trisomy 18, and more than 93% of fetuses with trisomy 13. This test can also evaluate sex chromosome conditions. A trisomy is a chromosome condition that occurs when there are 3 copies of a particular chromosome instead of 2. Trisomy 21 causes Down syndrome, trisomy 18 causes Edwards syndrome and trisomy 13 causes Patau syndrome.

Special Features


Twins – Twins pregnancies including IVF are eligible for Harmony (Trisomy 21,18,13) with or without Fetal Sex Option.

IVF – No restriction on pregnancies involving egg donor.


In additional to chromosomal abnormalities, you may screen for five microdeletion syndromes ( 22q11.2, 1p36, Cri-du-chat, Angelman, & Prader-Willi syndrome).

Panorama is the only NIPT that is validated to screen for triploidy.


  • Harmony

    Harmony is validated for pregnant women of any age or risk categories and trusted by clinicians worldwide. As early as 10 weeks, the Harmony Prenatal Test screens for the risk of Trisomy 21, 18 and 13.FIND OUT MORE
  • Panorama

    Panorama screens for genetic abnormalities of your baby as early as nine weeks of your pregnancy. Panorama can determine the sex of your baby and brings no risk to your baby.FIND OUT MORE


How does it work?

During pregnancy the placenta leaks cell-free DNA into the maternal bloodstream. As a result, a maternal blood sample containing a mixture of fetal and maternal circulating DNA may be used for NIPT.

Who can have the test?

The test is suitable for any pregnant woman who is of a gestation of 10 weeks or more. There is no upper limit on the gestation that the test can be done.

Sample requirements

A total of 20ml of blood from the mother will be needed.

How are the results reported?

Low Risk:  means that it is very unlikely your pregnancy is affected by trisomy 21, 18 or 13.

High risk:  means that your pregnancy is at increased risk for trisomy 21, 18 or 13 and the result should be confirmed by a follow up invasive procedure such as amniocentesis.

No result: In rare cases which insufficient fetal DNA or information was obtained to determine an accurate result, you may be asked by your healthcare provider for a redraw blood sample at no extra cost.

Can I avoid an invasive procedure altogether by having NIPT done?

This is not a diagnostic test. In the case which a ‘high risk’ result is indicated, an invasive procedure such as amniocentesis is recommended. Generally, only 1% of women will require such a procedure.

How long do the results take?

Results may take up to 14 days to be available.