ThinPrep Pap Test: How It Works and What to Expect

What is the ThinPrep Pap test?

The ThinPrep Pap test is an advanced cervical screening method used to detect abnormal, precancerous, or cancerous cells in the cervix. Also known as liquid-based cytology, it is a modern alternative to the conventional Pap smear, offering improved accuracy and clearer results.

It helps doctors find abnormal or cancer cells in the cervix before they turn into cancer.

Because of this enhanced sample preparation, the ThinPrep Pap test provides a higher chance of detecting abnormal cells, even in their earliest stages. It also reduces the likelihood of false negatives, helping healthcare professionals identify cervical cancer, precursor lesions and human papillomavirus (HPV)-related changes more reliably.

This test is widely recommended as part of regular women’s health screening, cervical cancer detection and is often performed alongside HPV DNA testing for a more comprehensive cervical cancer screening strategy. 

Who needs to do a ThinPrep Pap test?

The ThinPrep Pap test is recommended for anyone with a cervix between the ages of 21 and 65, especially those who are married, sexually active, or have been in the past. Regular cervical screening is key to detecting early signs of cervical cancer and preventing it from developing further.

Even if you feel healthy or have no symptoms, it’s still important to go for routine Pap tests, as cervical cell changes often don’t cause noticeable signs in the early stages.

Usually, healthcare guidelines generally recommend the ideal time as follows:

• Women aged 21 to 29:

  • Get a Pap test every 3 years.

• Women aged 30 to 65:

  • Get a Pap test every 3 years, or every 5 years if combined with HPV testing.

Women who have had the HPV vaccine should still continue regular screening, as the vaccine does not protect against all high-risk HPV types.

Therefore, you should always consult your doctor to decide the most suitable screening schedule based on your age, sexual history, medical background, and risk factors.

What is the difference between a Pap smear and a ThinPrep Pap test?

The ThinPrep Pap test is a more advanced and accurate version of the conventional method known as Pap smear. Both tests are used for cervical cancer screening and involve collection of cells from the cervix. However, the way the sample is prepared and analysed differs. 

Request an appointment with us to find out if the ThinPrep Pap test is right for you. Our specialists will provide a comprehensive explanation of the procedure, its benefits, and what you need to know to protect your cervical health.

How does the ThinPrep Pap test work?

The ThinPrep Pap test is a type of liquid-based cytology designed to improve how cervical cells are collected and analysed. It uses a special liquid solution to preserve the sample and create clearer, more reliable results.

• Cell collection: 

  • During a pelvic exam, your doctor gently collects cells from the cervix using a small brush or spatula. This part is quick and usually not painful.

• Preservation: 

  • Instead of placing the cells directly on a glass slide (as in a traditional Pap smear), the brush is rinsed into a vial containing a special liquid preservative. 

  • This helps to keep more cells intact and prevents them from drying out or getting damaged.

• Laboratory processing: 

  • The vial is sent to a laboratory, where the sample is cleaned to remove excess mucus, blood, or debris. A thin, even layer of cells is then placed onto a microscope slide.

• Cell analysis: 

  • A trained specialist, called a cytotechnologist, examines the slide under a microscope to check for abnormal cells, early signs of cervical cancer, or precancerous changes.

What do your ThinPrep Pap test results tell you?

The results of a ThinPrep Pap test can fall into several categories. Each result provides important information about the health of your cervix and whether further testing is needed: 

• Normal: 

  • No abnormal cells were found.

  • Until your next scheduled screening, no further action is required.

• Unclear:

  • The result is inconclusive.

  • This may happen due to inflammation, infection, or other factors. Your doctor may recommend a repeat test or additional screening.

• Abnormal: 

  • Changes in cervical cells were found, which could be precancerous or cancerous.

  • Further testing, such as HPV testing or colposcopy, may be required to determine the cause and appropriate next steps.

• Unsatisfactory: 

  • The sample did not contain enough cells or was obscured by mucus or blood.

  • You may need to repeat the test to obtain a clearer result.

Types of abnormal results

If your test result is abnormal, it doesn’t always mean cancer. It simply means that something unusual was found, and further evaluation is needed to understand what it is.

Some common abnormal findings include:

Are you worried about your results or in need of a screening? Request an appointment with our specialists at Thomson Medical to get the clarity and care you need.

ThinPrep Pap test in Singapore

In Singapore, the ThinPrep Pap Test has become the preferred method of cervical cancer screening in many public and private healthcare institutions. It offers a more accurate and reliable alternative to the traditional Pap smear, with improved sample quality and lower chances of false-negative results. 

Under Singapore’s national cervical cancer screening guidelines:

• Women aged 25 to 29 are recommended to undergo Pap testing every 3 years

• Women aged 30 to 69 are encouraged to take a HPV test every 5 years, which may be done alongside the ThinPrep method for greater accuracy

Many clinics in Singapore now use the ThinPrep system as the standard approach for Pap tests, especially when co-testing with HPV DNA testing.

Price of ThinPrep Pap test in Singapore

The cost of a ThinPrep Pap Test in Singapore varies depending on several factors. These include whether the test is done at a public or private facility, whether it includes HPV co-testing, and whether it forms part of a broader women's health screening package.

Several key factors can influence the overall cost. These include the need for specialist interpretation or follow-up, whether additional tests such as colposcopy are required after abnormal results, and whether pre-screening consultation or post-test reviews are included in the service.

At subsidised rates in public healthcare institutions

Eligible Singaporean women may access the ThinPrep Pap Test for as low as SGD 15 to SGD 40 under the Screen for Life (SFL) programme. This is applicable at participating CHAS clinics and selected polyclinics or public hospitals. For non-subsidised patients or referrals from private clinics, the cost may be higher.

At private clinics or hospitals

The price of a ThinPrep Pap test generally ranges from SGD 80 to SGD 200. This range depends on the inclusion of other services such as HPV DNA testing, specialist consultation, and whether the screening is part of a full gynaecological health check-up.

Patients may be able to use MediSave to offset part of the cost, particularly if the test is medically indicated or part of further diagnostic workup. As coverage limits and eligibility may differ between clinics, it is advisable to check with your healthcare provider or the relevant institution beforehand.

If you are due for a cervical cancer screening test or want to learn more about the ThinPrep Pap test, you can request an appointment with Thomson Medical. Our specialists will guide you through the procedure and help you understand your options, including any subsidies or packages available.

FAQ

Is the ThinPrep Pap test better than a traditional Pap smear?

Yes, the ThinPrep Pap test is generally more accurate. Instead of smearing the cells directly onto a slide, it preserves them in a liquid, allowing more cells to be examined clearly. This practice helps reduce errors and improves the chances of detecting abnormal cells early.

How long does the test take?

The ThinPrep Pap test takes only about 5 to 10 minutes. The entire visit may take a bit longer depending on consultation time, but the test itself is quick and done during a routine pelvic exam.

Is there any preparation needed before the test?

Yes, some basic preparation is recommended. You should avoid sexual intercourse, vaginal creams, douching, or using tampons for 24 to 48 hours before the test. It's also best to schedule the test when you're not on your period, as it may affect the results.

Is the ThinPrep Pap test painful?

The ThinPrep Pap test is not usually painful, but some people may feel slight discomfort during the procedure. You may also experience mild spotting or light vaginal bleeding afterwards, which typically goes away within a few days.

What is the difference between the HPV test and the ThinPrep Pap test?

The ThinPrep Pap test checks for abnormal or precancerous cells on the cervix, while the HPV test looks for the presence of high-risk human papillomavirus (HPV) types that can cause cervical cancer. Both tests use a sample of cervical cells, and they are often done together for more accurate screening. ThinPrep focuses on detecting cell changes, whereas the HPV test detects the virus that may cause those changes.

Does the ThinPrep Pap test check for STDs?

The ThinPrep Pap test is mainly used for cervical cancer screening and HPV. However, the same sample can sometimes be used to test for certain sexually transmitted infections (STIs), such as chlamydia and gonorrhoea, if your doctor requests it. On its own, the ThinPrep test does not automatically screen for all STIs.

How accurate is the ThinPrep Pap test?

The ThinPrep Pap test is highly accurate and more reliable than the traditional Pap smear. Its liquid-based method preserves more cervical cells and removes excess blood or mucus, allowing clearer analysis. This improves the chances of detecting abnormal or precancerous cells early and reduces the risk of false-negative results.

Are there any risks or side effects after the test?

The ThinPrep Pap test is generally safe. Some people may experience mild discomfort, light spotting, or slight cramping after the procedure. These symptoms usually go away within a day or two. Serious side effects are rare. If you experience heavy bleeding or prolonged pain, consult your doctor.

The information provided is intended for general guidance only and should not be considered medical advice. For personalised recommendations and tailored advice, please consult a specialist at Thomson Medical. Request an appointment with Thomson Medical today.